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Invitrogen
SARS-CoV-2 ORF3a (aa126-275), His Tag Recombinant Protein
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Product Details
RP-87667
Species
Expression System
Amino acid sequence
Tag
Molecular weight
Class
Type
Purity
Conjugate
Form
Purification
Storage buffer
Contains
Storage conditions
Shipping conditions
Product Specific Information
Purity is > 95% by SDS-PAGE.
Target Information
ORF3A forms homotetrameric potassium sensitive ion channels (viroporin) and may modulate virus release. Up-regulates expression of fibrinogen subunits FGA, FGB and FGG in host lung epithelial cells. Induces apoptosis in cell culture. Downregulates the type 1 interferon receptor by inducing serine phosphorylation within the IFN alpha-receptor subunit 1 (IFNAR1) degradation motif and increasing IFNAR1 ubiquitination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
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