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Gibco
Human sIL-15 Receptor alpha Fc Recombinant Protein, PeproTech®
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Product Details
200-15RA-100UG
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Amino acid sequence
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Product Specific Information
Recombinant Human sIL-15 Receptor alpha Fc has a calculated molecular weight of 44.4 kDa protein and contains 408 amino acid residues, which consists of the extracellular domain of IL-15R alpha fused to the Fc portion of human IgG. Due to glycosylation, it migrates at an apparent molecular weight of 50-60 kDa, under reducing conditions.
This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Target Information
Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CD215; IL 15 receptor; IL 15 receptor subunit α; IL 15R; IL 15R alpha; IL 15R α; IL-15 receptor subunit alpha; IL15 receptor; IL15 receptor subunit alpha; IL15 receptor subunit α; IL15R; IL15R alpha; IL15R α; Interleukin 15 receptor; interleukin 15 receptor alpha isoform EM2; interleukin 15 receptor alpha isoform IC2; interleukin 15 receptor alpha isoform IC3; interleukin 15 receptor alpha isoform IC4; interleukin 15 receptor alpha isoform IC5; interleukin 15 receptor alpha isoform IC6; interleukin 15 receptor alpha isoform IC7; interleukin 15 receptor alpha isoform IC8; Interleukin 15 receptor subunit α; interleukin 15 receptor, alpha; Interleukin-15 receptor subunit alpha; sIL 15R; sIL-15R-alpha; sIL-15RA; sIL15R; soluble IL 15R; soluble IL15R
Gene Aliases: CD215; IL15RA
UniProt ID: (Human) Q13261
Entrez Gene ID: (Human) 3601
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