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Invitrogen
Human VDP (aa 826-913) Control Fragment Recombinant Protein
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Product Details
RP-102821
Species
Expression System
Amino acid sequence
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Type
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Conjugate
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: General vesicular transport factor p115; Protein USO1 homolog; TAP; transcytosis associated protein; Transcytosis-associated protein; USO1 vesicle docking protein homolog; VDP p115; vesicle docking protein p115; Vesicle-docking protein
Gene Aliases: P115; TAP; USO1; VDP
UniProt ID: (Human) O60763
Entrez Gene ID: (Human) 8615
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