Invitrogen

Human TAGAP (aa 204-289) Control Fragment Recombinant Protein

Name: Human TAGAP (aa 204-289) Control Fragment Recombinant Protein
Brand: Invitrogen
SKU: RP-108828

View all (2) TAGAP proteins

Datasheet

Tech Support

Datasheet

Tech Support

Product Details

RP-108828

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

Blocking Assay (BLOCK)

Assay-dependent

Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

PNLLLLKHLVYVLHLISKNSEVNRMDSSNLAICIGPNMLTLENDQSLSFEAQKDLNNKVKTLVEFLIDNCFEIFGENIPVHSSITS

Tag

His-ABP-tag

Class

Recombinant

Type

Protein

Purity

>80% by SDS-PAGE and Coomassie blue staining

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

≥5.0 mg/mL

Purification

purified

Storage buffer

PBS/1M urea, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Product Specific Information

Highest antigen sequence indentity to the following orthologs: Mouse (87%), Rat (87%).

This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-139797. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Target Information

TAGAP (T-cell activation Rho GTPase-activating protein) is a 731 amino acid protein that contains one Rho-GAP domain and exists as 4 alternatively spliced isoforms. TAGAP may function as a GTPase-activating protein and may play important roles during T-cell activation. The gene that encodes TAGAP contains approximately 10,685 bases and maps to human chromosome 6q25.3. Making up nearly 6% of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, are also located on chromosome 6. In addition, Stickler syndrome, hydroxylase deficiency and maple syrup urine disease are associated with genes on chromosome 6, while a bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: T-cell activation GTPase-activating protein; T-cell activation Rho GTPase-activating protein