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Invitrogen
Human PRODH (aa 283-387) Control Fragment Recombinant Protein
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Product Details
RP-92348
Species
Expression System
Amino acid sequence
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Type
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Conjugate
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54187. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The protein encoded by this gene is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation. Defects in this gene are a cause of hyperprolinemia type 1 and possibly susceptibility to schizophrenia 4 (SCZD4). The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes DiGeorge syndrome and CATCH22 syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: p53-induced gene 6 protein; PRODH 1; PRODH 2; proline dehydrogenase (oxidase) 1; Proline dehydrogenase 1, mitochondrial; Proline oxidase; Proline oxidase 2; proline oxidase, mitochondrial; SCZD4; tumor protein p53 inducible protein 6
Gene Aliases: HSPOX2; PIG6; POX; POX2; PRODH; PRODH1; PRODH2; TP53I6
UniProt ID: (Human) Q6NV86
Entrez Gene ID: (Human) 5625
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