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Invitrogen
Human PPAPDC2 Synthetic Peptide
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Product Details
PEP-0979
Species Reactivity
Class
Type
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Product Specific Information
This peptide corresponds to 13 amino acids near the carboxy terminus of human PPAPDC2.
PEP-0979 can be used as a blocking peptide with polyclonal antibody PA5-20865.
Target Information
PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: FLJ46512; FLJ90191; Lipid phosphatase-related protein-B; LPRP-B; MGC15483; PA-PSP; phosphatidic acid phosphatase type 2 domain containing 2; Phosphatidic acid phosphatase type 2 domain-containing protein 2; Phospholipid phosphatase 6; polyisoprenoid diphosphate phosphatase type 1; Polyisoprenoid diphosphate/phosphate phosphohydrolase PLPP6; PPAP2 domain-containing protein 2; Presqualene diphosphate phosphatase; RP11-6J24.2; Type 1 polyisoprenoid diphosphate phosphatase
Gene Aliases: bA6J24.6; PDP1; PLPP6; PPAPDC2; PSDP
UniProt ID: (Human) Q8IY26
Entrez Gene ID: (Human) 403313
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