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Invitrogen
Human MATN2 Synthetic Peptide
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Product Details
PEP-0848
Species Reactivity
Class
Type
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Product Specific Information
This peptide corresponds to 15 amino acids near the carboxy terminus of human MATN2.
PEP-0848 can be used as a blocking peptide with polyclonal antibody PA5-20734.
Target Information
Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. The matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation and diseases such as astrocytoma and liver carcinoma. Recent studies show that MATN2 is a permissive substrate for axonal growth and cell migration, and it is required for successful nerve regeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Matrilin-2; testis tissue sperm-binding protein Li 94mP
Gene Aliases: MATN2; UNQ193/PRO219
UniProt ID: (Human) O00339
Entrez Gene ID: (Human) 4147
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