Invitrogen

Human MAPK11 (p38 beta), His Tag Recombinant Protein

Name: Human MAPK11 (p38 beta), His Tag Recombinant Protein
Brand: Invitrogen
SKU: PV3679

View all (3) p38 MAPK beta proteins

Datasheet

Tech Support

Datasheet

Tech Support

Product Details

PV3679

Applications

Tested Dilution

Publications

Kinase Assay (KA)

Assay-dependent

Product Specifications

Species

Human

Expression System

Insect cells

Amino acid sequence

Full length

Tag

His-tag

Molecular weight

47.2 kDa

Class

Recombinant

Type

Protein

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

purified

Storage buffer

50mM tris, pH 7.5, with 2mM DTT, 150mM NaCl, 0.5mM EDTA, 0.02% Triton X-100, 50% glycerol

Contains

no preservative

Storage conditions

-80°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Dry ice

Product Specific Information

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 µg, 10 µg and 20 µg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 µL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase.

Protein Form: Full Length

Target Information

MAPK11 (p38 beta) is a serine/threonine kinase which is involved in a variety of cellular processes, and is activated by proinflammatory cytokines and environmental stress. Mitogen-activated protein kinase 11. The protein encoded by p38 MAPK beta is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. This kinase is most closely related to p38 MAP kinase, both of which can be activated by proinflammatory cytokines and environmental stress. This kinase is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: MAP kinase 11; MAP kinase p38 beta; Mitogen-activated protein kinase 11; Mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; OTTHUMP00000196655; p38-2; SAPK2b; Stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b