Invitrogen

Human MAGEA9 (aa 50-74) Control Fragment Recombinant Protein

Name: Human MAGEA9 (aa 50-74) Control Fragment Recombinant Protein
Brand: Invitrogen
SKU: RP-108886
Availability: InStock

Datasheet

Tech Support

Datasheet

Tech Support

Product Details

RP-108886

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

Blocking Assay (BLOCK)

Assay-dependent

Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

SAAGSSSPPQSPQGGASSSISVYYT

Tag

His-ABP-tag

Class

Recombinant

Type

Protein

Purity

>80% by SDS-PAGE and Coomassie blue staining

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

≥5.0 mg/mL

Purification

purified

Storage buffer

PBS/1M urea, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Product Specific Information

Highest antigen sequence indentity to the following orthologs: Mouse (46%), Rat (46%).

This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-139813. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Target Information

MAGEA9 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80% sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Cancer/testis antigen 1.9; cancer/testis antigen family 1, member 9; CT1.9; MAGE-9 antigen; melanoma antigen family A, 9; melanoma antigen family A9; Melanoma-associated antigen 9