Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Human JRK Control Fragment Recombinant Protein
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
RP-106407
Species
Expression System
Amino acid sequence
Tag
Class
Type
Purity
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (45%), Rat (45%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-65735. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The JRK gene encodes a protein known as JRK (Jerky) homolog, which is implicated in various cellular processes, including DNA damage response and transcription regulation. JRK is conserved across multiple species and plays a role in the stability of neuronal functions and development. It is notably associated with neuropsychiatric disorders, where aberrations in its expression or function can contribute to conditions such as epilepsy and intellectual disabilities. The protein interacts with other cellular components to influence gene expression patterns, which are critical for maintaining normal neuronal activity. JRK is also studied for its potential involvement in cancer biology, where it may impact cell cycle regulation and genomic stability. Understanding the functions and mechanisms of JRK can provide insights into its roles in both normal physiological processes and disease states, particularly in the context of the nervous system and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: jerky homolog; Jerky protein homolog; Jrk homolog
Gene Aliases: jerky; JH8; JRK
UniProt ID: (Human) O75564
Entrez Gene ID: (Human) 8629
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support