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Invitrogen
Human JLP (aa 694-771) Control Fragment Recombinant Protein
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Product Details
RP-107069
Species
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Amino acid sequence
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (94%), Rat (94%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-111525. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate. Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: c-Jun NH2-terminal kinase-associated leucine zipper protein; C-Jun-amino-terminal kinase-interacting protein 4; Cancer/testis antigen 89; CT89; HLC-6; Human lung cancer oncogene 6 protein; JIP-4; JLP; JNK interacting protein; JNK-associated leucine-zipper protein; JNK/SAPK-associated protein; lung cancer oncogene 4; Max-binding protein; Mitogen-activated protein kinase 8-interacting protein 4; PHET; proliferation-inducing gene 6; Proliferation-inducing protein 6; Protein highly expressed in testis; sperm associated antigen 9 variant 5; Sperm surface protein; Sperm-associated antigen 9; Sperm-specific protein; Sunday driver 1
Gene Aliases: CT89; HLC-6; HLC4; HLC6; HSS; JIP-4; JIP4; JLP; KIAA0516; MAPK8IP4; PHET; PIG6; SPAG9; SYD1
UniProt ID: (Human) O60271
Entrez Gene ID: (Human) 9043
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