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Invitrogen
Human DUS2L (aa 101-210) Control Fragment Recombinant Protein
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Product Details
RP-98737
Species
Expression System
Amino acid sequence
Tag
Class
Type
Purity
Conjugate
Form
Concentration
Purification
Storage buffer
Contains
Storage conditions
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (93%), Rat (93%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60405. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 [PubMed 15994936]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Dihydrouridine synthase 2; dihydrouridine synthase 2-like, SMM1 homolog; hDUS2; SMM1 homolog; tRNA-dihydrouridine synthase 2-like; tRNA-dihydrouridine(20) synthase (NAD(P)(+)); tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Up-regulated in lung cancer protein 8; URLC8
Gene Aliases: DUS2; DUS2L; SMM1; URLC8
UniProt ID: (Human) Q9NX74
Entrez Gene ID: (Human) 54920
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