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Invitrogen
Human DUOX1 Control Fragment Recombinant Protein
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Product Details
RP-91278
Species
Expression System
Amino acid sequence
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Type
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Conjugate
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (84%), Rat (84%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54817. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Dual oxidase 1; flavoprotein NADPH oxidase; Large NOX 1; Long NOX 1; NADPH thyroid oxidase 1; nicotinamide adenine dinucleotide phosphate oxidase; Thyroid oxidase 1
Gene Aliases: DUOX; DUOX1; LNOX1; NOXEF1; THOX1
UniProt ID: (Human) Q9NRD9
Entrez Gene ID: (Human) 53905
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