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Invitrogen
Human DOK2 (aa 340-412) Control Fragment Recombinant Protein
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Product Details
RP-108235
Species
Expression System
Amino acid sequence
Tag
Class
Type
Purity
Conjugate
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Purification
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (66%), Rat (66%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-84732. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Docking protein 2; docking protein 2, 56kD; docking protein 2, 56kDa; Downstream of tyrosine kinase 2; p56(dok-2)
Gene Aliases: DOK2; p56DOK; p56dok-2
UniProt ID: (Human) O60496
Entrez Gene ID: (Human) 9046
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