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Invitrogen
Human DMRT1 (aa 235-369) Control Fragment Recombinant Protein
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Product Details
RP-100719
Species
Expression System
Amino acid sequence
Tag
Class
Type
Purity
Conjugate
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Purification
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (77%), Rat (77%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-55713. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: DM domain expressed in testis 1; DM domain expressed in testis protein 1; Doublesex- and mab-3-related transcription factor 1
Gene Aliases: CT154; DMRT1; DMT1
UniProt ID: (Human) Q9Y5R6
Entrez Gene ID: (Human) 1761
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