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Invitrogen
Human DLC1 (aa 8-133) Control Fragment Recombinant Protein
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Product Details
RP-90818
Species
Expression System
Amino acid sequence
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Conjugate
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (68%), Rat (68%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53635. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
This gene encodes a GTPase-activating protein that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: ARHGAP 7; Deleted in liver cancer 1 protein; deleted in liver cancer 1 variant 2; deleted in liver cancer variant 4; DLC 1; DLC-1; FLJ21120; HP protein; p122 RhoGAP; Rho GTPase-activating protein 7; Rho-GTPase-activating protein 7; Rho-type GTPase-activating protein 7; StAR-related lipid; StAR-related lipid transfer (START) domain containing 12; StAR-related lipid transfer protein 12; STARD 12; StARD12; START domain-containing protein 12; transfer protein 12
Gene Aliases: ARHGAP7; DLC1; HP; KIAA1723; p122-RhoGAP; STARD12
UniProt ID: (Human) Q96QB1
Entrez Gene ID: (Human) 10395
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