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Invitrogen
Human DGCR2 (aa 455-549) Control Fragment Recombinant Protein
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Product Details
RP-108063
Species
Expression System
Amino acid sequence
Tag
Class
Type
Purity
Conjugate
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Purification
Storage buffer
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Storage conditions
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (83%), Rat (83%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-67399. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
Deletions of the 22q11.2 have been associated with a wide range of developmental defects (notably DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome and isolated conotruncal cardiac defects) classified under the acronym CATCH 22. The DGCR2 gene encodes a novel putative adhesion receptor protein, which could play a role in neural crest cells migration, a process which has been proposed to be altered in DiGeorge syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: DiGeorge syndrome critical region protein 2; integral membrane protein deleted in DiGeorge syndrome; Integral membrane protein DGCR2/IDD
Gene Aliases: DGCR2; DGS-C; IDD; KIAA0163; LAN; SEZ-12
UniProt ID: (Human) P98153
Entrez Gene ID: (Human) 9993
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