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Invitrogen
Human CTAG2 Control Fragment Recombinant Protein
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Product Details
RP-104301
Species
Expression System
Amino acid sequence
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Conjugate
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (30%), Rat (30%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-64462. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
CTAG2 encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Autoimmunogenic cancer/testis antigen NY-ESO-2; Cancer/testis antigen 2; Cancer/testis antigen 6.2; cancer/testis antigen family 6, member 2a; cancer/testis antigen family 6, member 2b; CT2; CT6.2; CT62; CTL-recognized antigen on melanoma; L antigen family member 1; LAGE-1; LAGE-1a protein
Gene Aliases: CAMEL; CT2; CT6.2; CT6.2a; CT6.2b; CTAG2; ESO2; LAGE-1; LAGE1; LAGE2B
UniProt ID: (Human) O75638
Entrez Gene ID: (Human) 30848
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