Invitrogen

Human COX7A2L (aa 3-76) Control Fragment Recombinant Protein

Name: Human COX7A2L (aa 3-76) Control Fragment Recombinant Protein
Brand: Invitrogen
SKU: RP-106919

Datasheet

Tech Support

Datasheet

Tech Support

Product Details

RP-106919

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

Blocking Assay (BLOCK)

Assay-dependent

Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

YKFSGFTQKLAGAWASEAYSPQGLKPVVSTEAPPIIFATPTKLTSDSTVYDYAGKNKVPELQKFFQKADGVPVY

Tag

His-ABP-tag

Class

Recombinant

Type

Protein

Purity

>80% by SDS-PAGE and Coomassie blue staining

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

≥5.0 mg/mL

Purification

purified

Storage buffer

1M urea/PBS, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Product Specific Information

Highest antigen sequence indentity to the following orthologs: Mouse (85%), Rat (85%).

This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-66237. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Target Information

The cytochrome c oxidase (COX) family of proteins function as the final electron donor in the respiratory chain to drive a proton gradient across the inner mitochondrial membrane, ultimately resulting in the production of water. The mammalian COX apoenzyme is a dimer, with each monomer consisting of 13 subunits, some of which are mitochondrial and some of which are nuclear. COX7a2 (cytochrome c oxidase subunit VIIa polypeptide 2), also known as COX7AL or COX7AL1, is an 83 amino acid protein that localizes to the inner mitochondrial membrane and exists as a component of the COX complex, playing an important role in electron transport. COX7a2L (cytochrome c oxidase subunit 7A-related protein), also known as COX7AR or COX7RP, is an inner mitochondrial membrane protein that consists of 114 amino acids and is induced by estrogen.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: COX7a-related protein; Cytochrome c oxidase subunit 7A-related protein; Cytochrome c oxidase subunit 7A2-like, mitochondrial; cytochrome c oxidase subunit VII-related protein; cytochrome c oxidase subunit VIIa polypeptide 2 like; Cytochrome c oxidase subunit VIIa-related protein; EB1; estrogen receptor binding CpG island; Supercomplex assembly factor 1