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Invitrogen
Human CNPY3 Control Fragment Recombinant Protein
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Product Details
RP-91634
Species
Expression System
Amino acid sequence
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Conjugate
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-53443. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
PRAT4A is a novel protein belonging to the canopy family with a saposin B-type domain. It is an accessory molecule required for microbial recognition by Toll-like receptor (TLR), and mediates TLR dependent immune responses. Though the exact function of PRAT4A is still unknown, reports suggest that it is associated with the immature form of TLR4 and regulates the cell surface expression of this TLR. PRAT4A, a secreted protein, also has a role in TLR4 maturation and glycosylation. PRATA4 is usually present in endoplasmic reticulum and plays an active role in regulating the subcellular distribution and response of multiple TLRs and is required for both innate and adaptive immune responses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CAG repeat containing; CAG/CTG 5; CTG repeat protein 4a; Expanded repeat-domain protein CAG/CTG 5; Protein associated with TLR4; protein associated with Toll-like receptor 4A; Protein canopy homolog 3; Trinucleotide repeat-containing gene 5 protein
Gene Aliases: CAG4A; CNPY3; CTG4A; ERDA5; HSPC084; PRAT4A; TNRC5; UNQ1934/PRO4409
UniProt ID: (Human) Q9BT09
Entrez Gene ID: (Human) 10695
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