Invitrogen

Human CD27L (TNFSF7) Fc Chimera Recombinant Protein

Name: Human CD27L (TNFSF7) Fc Chimera Recombinant Protein
Brand: Invitrogen
SKU: RP-88013
Availability: InStock

View all (3) CD70 proteins

Datasheet

Tech Support

Datasheet

Tech Support

Testing Data (1)

Human CD27L (TNFSF7) Fc Chimera Protein in SDS-PAGE (SDS-PAGE)

FIGURE: 1 / 1

Human CD27L (TNFSF7) Fc Chimera Protein (RP-88013) in SDS-PAGE

SDS-PAGE analysis of Human CD27L (TNFSF7) Fc Chimera (Product # RP-88013) shows purity to be: > 90 % (SDS-PAGE).

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Product Details

RP-88013

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

Product Specifications

Species

Human

Expression System

HEK293 cells

Amino acid sequence

Human CD27L, amino acids Gln39-Pro193 (Accession # NP_001243.1) with an N-terminal human IgG1 Fc region

Tag

Fc-tag

Molecular weight

45.5 kDa

Class

Recombinant

Type

Protein

Purity

>90% as determined by SDS-PAGE.

Endotoxin concentration

<1.0 EU/µg

Activity

Measured by its binding ability in a functional ELISA. Immobilized Human CD27 His at 2 µg/ml (100 µL/well) can bind Human CD70 hFc, the EC50 of Human CD70 hFc is 15-60 ng/mL.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Storage buffer

PBS, pH 7.4, with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

It is recommended that the protein be aliquoted for optimal storage.

It is recommended that sterile water (450 µL) be added to the vial to prepare a stock solution of 2.22 mg/mL.

Concentration is measured by UV.

Target Information

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: CD27 ligand; CD27-L; CD70; CD70 antigen; Ki-24 antigen; surface antigen CD70; tumor necrosis factor (ligand) superfamily, member 7; tumor necrosis factor ligand 8A; Tumor necrosis factor ligand superfamily member 7