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Invitrogen
Human CD151 (aa 118-215) Control Fragment Recombinant Protein
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Product Details
RP-90649
Species
Expression System
Amino acid sequence
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Type
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Conjugate
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (88%), Rat (88%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-82439. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It is involved in cellular processes including cell adhesion and may regulate integrin trafficking and/or function. This protein enhances cell motility, invasion and metastasis of cancer cells. Multiple alternatively spliced transcript variants that encode the same protein have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: CD 151; CD151; CD151 antigen; CD151 antigen (Raph blood group); CD151 molecule; GP27; hemidesmosomal tetraspanin CD151; Membrane glycoprotein SFA-1; PETA-3; platelet surface glycoprotein gp27; platelet-endothelial cell tetraspan antigen 3; Platelet-endothelial tetraspan antigen 3; Tetraspanin-24; Tspan-24
Gene Aliases: CD151; GP27; MER2; PETA-3; RAPH; SFA1; TSPAN24
UniProt ID: (Human) P48509
Entrez Gene ID: (Human) 977
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