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Gibco

Human CCL22 (MDC) Recombinant Protein

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Datasheet
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Datasheet
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Cite Human CCL22 (MDC) Recombinant Protein

Product Details

PHC1204

Applications
Tested Dilution
Publications

Western Blot (WB)

Assay-dependent
-

Immunohistochemistry (IHC)

Assay-dependent
-

ELISA (ELISA)

Assay-dependent
-

Functional Assay (Functional)

Assay-dependent
-

Control (Ctrl)

Assay-dependent
-
Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

Human CCL22 recombinant protein contains 67 amino acids

Molecular weight

8 kDa

Class

Recombinant

Type

Protein

Purity

>98% by SDS-PAGE

Endotoxin concentration

<0.1 ng/µg

Activity

ED50 = 10-100 ng/mL; determined by the dose-dependent chemotaxis of human T-cells.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Wet or Dry ice (international)

Product Specific Information

Carrier-Free

Reconstitution: The vial should be centrifuged prior to opening to bring contents to the bottom. The lyophilized powder should be reconstituted with sterile, distilled water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2°C to 8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein, such as 0.1% BSA and store in working aliquots at -20°C to -80°C.

Storage: The lyophilized protein is stable at room temperature for 1 month, but should be kept at -20°C for long term storage. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C. Avoid repeated freeze/thaw cycles. Avoid repeated freeze/thaw cycles.

Target Information

CCL22 may play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Also, it is a chemotactic for monocytes. dendritic cells and natural killer cells. CCL22 is a mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AW060611; C-C motif chemokine 22; CC chemokine STCP-1; chemokine (C-C motif) ligand 22; Macrophage-derived chemokine; MDC(1-69); MGC108943; MGC34554; RP24-69A20.1; small inducible cytokine A22; small inducible cytokine subfamily A (Cys-Cys), member 22; Small-inducible cytokine A22; stimulated T cell chemotactic protein 1; Stimulated T-cell chemotactic protein 1

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Gene Aliases: A-152E5.1; ABCD-1; CCL22; DC/B-CK; MDC; SCYA22; STCP-1

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UniProt ID: (Human) O00626

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Entrez Gene ID: (Human) 6367

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It has to be done as per old AB suggested Products section.
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