Invitrogen

Human Bit1 Synthetic Peptide

Name: Human Bit1 Synthetic Peptide
Brand: Invitrogen
SKU: PEP-0285
Availability: InStock

View all (3) Bit1 proteins

Datasheet

Tech Support

Datasheet

Tech Support

Product Details

PEP-0285

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

Blocking Assay (BLOCK)

Assay-dependent

Product Specifications

Species Reactivity

Human

Class

Synthetic

Type

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

purified

Storage buffer

PBS, pH 7.2, with 0.1% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

This peptide corresponds to 16 amino acids near the center terminus of human Bit1.

PEP-0285 can be used as a blocking peptide with polyclonal antibody PA5-20168.

Target Information

The protein encoded by this gene is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix characterized by intellectual disability, postnatal microcephaly, progressive cerebellar atrophy, hearing impairment, polyneuropathy, failure to thrive, and organ fibrosis with exocrine pancreas insufficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: Bcl-2 inhibitor of transcription 1; cilia and flagella associated protein 37; OTTHUMP00000205936; Peptidyl-tRNA hydrolase 2, mitochondrial; PTH 2