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Invitrogen
Human BMP6 (aa 363-418) Control Fragment Recombinant Protein
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Product Details
RP-107183
Species
Expression System
Amino acid sequence
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Class
Type
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Conjugate
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Purification
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Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%).
This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
BMP6 is a member of bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, Bmp6 has a proposed role in early development. In addition, the fact that BMP6 is closely related to BMP5 and BMP7 has lead to speculation of possible bone inductive activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: BMP; BMP 6; BMP-6; Bone morphogenetic protein; Bone morphogenetic protein 6; vegetal related growth factor (TGFB-related); vegetal-related (TGFB related) cytokine; VG-1-R; VG-1-related protein; Vg1-related sequence; VGR-1
Gene Aliases: BMP6; VGR; VGR1
UniProt ID: (Human) P22004
Entrez Gene ID: (Human) 654
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