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Invitrogen
Human BEX2 (aa 27-54) Control Fragment Recombinant Protein
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Product Details
RP-99266
Species
Expression System
Amino acid sequence
Tag
Class
Type
Purity
Conjugate
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Concentration
Purification
Storage buffer
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Storage conditions
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (52%), Rat (52%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-60988. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
This gene belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. This gene has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Brain-expressed X-linked protein 2; hBex2; Protein BEX2; RP1-79P11.1
Gene Aliases: BEX1; BEX2; DJ79P11.1
UniProt ID: (Human) Q9BXY8
Entrez Gene ID: (Human) 84707
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