Invitrogen

Human ATP11A Synthetic Peptide

Name: Human ATP11A Synthetic Peptide
Brand: Invitrogen
SKU: PEP-1109

View all (3) ATP11A proteins

Datasheet

Tech Support

Datasheet

Tech Support

Product Details

PEP-1109

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

Blocking Assay (BLOCK)

Assay-dependent

Product Specifications

Species Reactivity

Human

Class

Synthetic

Type

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

200 µg/mL

Purification

purified

Storage buffer

PBS, pH 7.2, with 0.1% BSA

Contains

0.02% sodium azide

Storage conditions

-20°C

Product Specific Information

This peptide corresponds to 19 amino acids near the amino terminus of human ATP11A.

PEP-1109 can be used as a blocking peptide with polyclonal antibody PA5-20995.

Target Information

ATP11A is a widely expressed integral membrane ATPase. ATP11A is probably phosphorylated in its intermediate state and likely drives the transport of ions such as calcium or other molecules across membranes. While the exact molecule ATP11A transports is unknown, increased expression of ATP11A mRNA has been observed in murine leukemia cells made resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs). Furthermore, overexpression of ATP11A provided protection against the FTI SCH66336 while knockdown of ATP11A via siRNA made cells more sensitive to this drug. Other reports suggest that elevated levels of ATP11A mRNA may also be a predictive marker of metastasis in colorectal cancer patients.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: ATPase class VI type 11A; ATPase IS; ATPase, class VI, type 11A; P4-ATPase flippase complex alpha subunit ATP11A; phospholipid-translocating ATPase; Phospholipid-transporting ATPase IH; potential phospholipid-transporting ATPase IH; RP11-120K24.1