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Invitrogen
Human ANKK1 (aa 319-459) Control Fragment Recombinant Protein
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Product Details
RP-89809
Species
Expression System
Amino acid sequence
Tag
Class
Type
Purity
Conjugate
Form
Concentration
Purification
Storage buffer
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Storage conditions
Product Specific Information
Highest antigen sequence indentity to the following orthologs: Mouse (74%), Rat (74%).
This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-52987. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Target Information
ANKK1 serine/threonine kinase is a member of the RIPK family and is closely linked to the DRD2 gene. ANKK1 is closely linked to DRD2 gene on chr 11, and a well studied restriction fragment length polymorphism designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene, where it causes a nonconservative amino acid substitution. It is not clear if ANKK1 plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Bioinformatics
Protein Aliases: Ankyrin repeat and protein kinase domain-containing protein 1; Protein kinase PKK2; SgK288; Sugen kinase 288; X-kinase
Gene Aliases: ANKK1; PKK2; SGK288
UniProt ID: (Human) Q8NFD2
Entrez Gene ID: (Human) 255239
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