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  • AARS2 Proteins

Invitrogen

Human AARS2 (aa 635-708) Control Fragment Recombinant Protein

View all (2) AARS2 proteins

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Datasheet
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Datasheet
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Cite Human AARS2 (aa 635-708) Control Fragment Recombinant Protein

Product Details

RP-94748

Applications
Tested Dilution
Publications

Control (Ctrl)

Assay-dependent
-

Blocking Assay (BLOCK)

Assay-dependent
-
Product Specifications

Species

Human

Expression System

E. coli

Amino acid sequence

THLLNWALRQTLGPGTEQQGSHLNPEQLRLDVTTQTPLTPEQLRAVENTVQEAVGQDEAVYMEEVPLALTAQVP

Tag

His-ABP-tag

Class

Recombinant

Type

Protein

Purity

>80% by SDS-PAGE and Coomassie blue staining

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

≥5.0 mg/mL

Purification

purified

Storage buffer

PBS/1M urea, pH 7.4

Contains

no preservative

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

Highest antigen sequence indentity to the following orthologs: Mouse (76%), Rat (76%).

This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-57347. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.

Target Information

The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: AARS2; alanine tRNA ligase 2, mitochondrial (putative); Alanine--tRNA ligase, mitochondrial; Alanyl-tRNA synthetase; alanyl-tRNA synthetase 2, mitochondrial (putative); alanyl-tRNA synthetase like; AlaRS; bA444E17.1; probable alanyl-tRNA synthetase, mitochondrial; Protein lactyltransferase AARS2

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Gene Aliases: AARS2; AARSL; COXPD8; KIAA1270; LKENP; MT-ALARS; MTALARS

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UniProt ID: (Human) Q5JTZ9

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Entrez Gene ID: (Human) 57505

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It has to be done as per old AB suggested Products section.
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