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Gene Symbol:
Pcsk9
Gene Name:
proprotein convertase subtilisin/kexin type 9
Gene Aliases:
AI415265, AI747682, FH3, HCHOLA3, Narc1, PC9
Chromosome Location:
Chr.4: 106442334 - 106464325 on Build GRCm38
UniGene ID:
Mm.133268
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID s97531

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Catalog # 4390771
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: Pcsk9
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_153565.2 NP_705793.1 2 759
GenBank mRNA AK043077.1 - 2 609
AK149520.1 - 2 538
AY273821.1 - 2 383
BC038085.1 - 2 774 4502199

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More Information


Panther Classification:

Molecular Function -

serine protease

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of receptor recycling
positive regulation of receptor internalization
proteolysis
lipid metabolic process
triglyceride metabolic process
phospholipid metabolic process
apoptotic process
lysosomal transport
steroid metabolic process
cholesterol metabolic process
cellular response to starvation
regulation of receptor activity
negative regulation of low-density lipoprotein particle clearance
protein processing
protein autoprocessing
neuron differentiation
low-density lipoprotein receptor particle metabolic process
low-density lipoprotein particle receptor catabolic process
regulation of low-density lipoprotein particle receptor catabolic process
positive regulation of low-density lipoprotein particle receptor catabolic process
cellular response to insulin stimulus
lipoprotein metabolic process
cholesterol homeostasis
regulation of neuron apoptotic process
positive regulation of neuron apoptotic process
negative regulation of receptor activity
negative regulation of sodium ion transmembrane transporter activity
serine-type endopeptidase activity
peptidase activity
serine-type peptidase activity
hydrolase activity
sodium channel inhibitor activity
low-density lipoprotein particle binding
receptor inhibitor activity
apolipoprotein binding
very-low-density lipoprotein particle binding
apolipoprotein receptor binding
protein self-association
poly(A) RNA binding
low-density lipoprotein particle receptor binding
very-low-density lipoprotein particle receptor binding

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