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Gene Symbol:
Dock2
Gene Name:
dedicator of cyto-kinesis 2
Gene Aliases:
AI662014, AW122239, CED-5, Hch, MBC
Chromosome Location:
Chr.11: 34226815 - 34514545 on Build GRCm38
UniGene ID:
Mm.380679
Species:
Mouse
Species Specific ID (Flybase ID):
-
siRNA ID s96991

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Catalog # 4390771
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: Dock2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_033374.3 NP_203538.2 4629
GenBank mRNA AK085708.1 - 47
AK172915.1 - 3765
AY027438.1 - 4547

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_008767630.

Gene Ontology Categories:

Function(s) Process(es)

membrane raft polarization
establishment of T cell polarity
immunological synapse formation
myeloid dendritic cell activation involved in immune response
chemotaxis
cytoskeleton organization
small GTPase mediated signal transduction
positive regulation of Rac protein signal transduction
T cell proliferation
T cell activation
positive regulation of GTPase activity
macropinocytosis
positive thymic T cell selection
negative thymic T cell selection
alpha-beta T cell activation
alpha-beta T cell proliferation
positive regulation of phagocytosis
guanyl-nucleotide exchange factor activity
GTPase activator activity
Rac guanyl-nucleotide exchange factor activity
T cell receptor binding

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