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Gene Symbol:
MSH2
Gene Name:
mutS homolog 2
Gene Aliases:
COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Chromosome Location:
Chr.2: 47403067 - 47634501 on Build GRCh38
UniGene ID:
Hs.597656
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s8968

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Catalog # 4392420
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: MSH2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000251.2 NP_000242.1 15 2708
NM_001258281.1 NP_001245210.1 16 2524
XM_005264332.3 XP_005264389.2 15 2655
XM_011532867.1 XP_011531169.1 15 2655
GenBank mRNA AK222860.1 - 15 2645
AK223284.1 - 15 2618
AK296831.1 - 14 2183
AK297763.1 - 15 2411
AK299667.1 - 14 2043
AK304496.1 - 16 2524
BC021566.1 - 15 2597 4110354
BX649122.1 - 15 2603
L47574.1 - 15 2623
L47575.1 - 15 2621
L47576.1 - 15 2622
L47577.1 - 15 2623
L47578.1 - 15 2624
L47579.1 - 15 2624
L47580.1 - 15 2622
L47581.1 - 15 2623
L47582.1 - 15 2623
L47583.1 - 15 2623
U03911.1 - 15 2586
U04045.1 - 15 2651

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More Information


Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Function(s) Process(es)

meiotic mismatch repair
in utero embryonic development
oxidative phosphorylation
DNA repair
mismatch repair
postreplication repair
double-strand break repair
meiotic gene conversion
cell cycle arrest
reciprocal meiotic recombination
germ cell development
determination of adult lifespan
male gonad development
response to X-ray
response to UV-B
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
B cell mediated immunity
B cell differentiation
intra-S DNA damage checkpoint
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of neuron apoptotic process
maintenance of DNA repeat elements
negative regulation of reciprocal meiotic recombination
isotype switching
negative regulation of DNA recombination
positive regulation of helicase activity
magnesium ion binding
four-way junction DNA binding
Y-form DNA binding
heteroduplex DNA loop binding
double-strand/single-strand DNA junction binding
DNA binding
double-stranded DNA binding
single-stranded DNA binding
protein binding
ATP binding
protein C-terminus binding
ATPase activity
centromeric DNA binding
enzyme binding
protein kinase binding
mismatched DNA binding
guanine/thymine mispair binding
dinucleotide insertion or deletion binding
single guanine insertion binding
single thymine insertion binding
dinucleotide repeat insertion binding
oxidized purine DNA binding
MutLalpha complex binding
protein homodimerization activity
ADP binding

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