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Gene Symbol:
MCL1
Gene Name:
BCL2 family apoptosis regulator
Gene Aliases:
BCL2L3, EAT, MCL1-ES, MCL1L, MCL1S, Mcl-1, TM, bcl2-L-3, mcl1/EAT
Chromosome Location:
Chr.1: 150574551 - 150579738 on Build GRCh38
UniGene ID:
Hs.632486
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s8584

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Catalog # 4392420
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: MCL1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001197320.1 NP_001184249.1 4 714
NM_021960.4 NP_068779.1 3 1173
NM_182763.2 NP_877495.1 2 925
GenBank mRNA AF118124.1 - 3 1014
AF203373.1 - 2 717
AK294462.1 - 4 745
AK297217.1 - 4 709
AK300499.1 - 4 819
AK304775.1 - 4 855
AK312508.1 - 3 1045
AK316267.1 - 4 1001
BC017197.2 - 3 1019 3138465
BC071897.1 - 3 1021 6586159
BC107735.1 - 3 1036 4770487
BT006640.1 - 3 965
L08246.1 - 3 1025

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More Information


Gene Ontology Categories:

Function(s) Process(es)

cell fate determination
multicellular organism development
intrinsic apoptotic signaling pathway in response to DNA damage
apoptotic mitochondrial changes
cellular homeostasis
response to cytokine
negative regulation of apoptotic process
protein transmembrane transport
extrinsic apoptotic signaling pathway in absence of ligand
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
negative regulation of anoikis
regulation of response to DNA damage stimulus
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
negative regulation of intrinsic apoptotic signaling pathway
protein binding
protein channel activity
protein homodimerization activity
protein heterodimerization activity
BH3 domain binding

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