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Gene Symbol:
LCK
Gene Name:
LCK proto-oncogene, Src family tyrosine kinase
Gene Aliases:
IMD22, LSK, YT16, p56lck, pp58lck
Chromosome Location:
Chr.1: 32251239 - 32286167 on Build GRCh38
UniGene ID:
Hs.470627
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s8106

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Catalog # 4392420
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: LCK
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001042771.2 NP_001036236.1 5, 6 499
NM_005356.4 NP_005347.3 5, 6 516
XM_011541453.2 XP_011539755.1 4, 5 690
XM_011541454.2 XP_011539756.1 4, 5 671
XM_011541455.2 XP_011539757.1 5, 6 516
GenBank mRNA AF228313.1 - 4, 5 339
AJ865079.1 - 3, 4 552
AK303073.1 - 4, 5 569
BC013200.1 - 5, 6 478 4341278
DA007906.1 - 5, 6 516
DB122062.1 - 5, 6 500
DB129997.1 - 5, 6 437
KU178161.1 - 4, 5 378
KU178162.1 - 4, 5 378
KU178163.1 - 4, 5 378
M36881.1 - 5, 6 429
U07236.1 - 5, 6 404
X05027.1 - 5, 6 470
X13529.1 - 5, 6 429

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More Information


Gene Ontology Categories:

Function(s) Process(es)

protein phosphorylation
protein dephosphorylation
cellular zinc ion homeostasis
activation of cysteine-type endopeptidase activity involved in apoptotic process
transmembrane receptor protein tyrosine kinase signaling pathway
regulation of phosphatidylinositol 3-kinase signaling
viral process
hemopoiesis
platelet activation
T cell differentiation
T cell costimulation
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
response to drug
innate immune response
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
regulation of defense response to virus by virus
T cell receptor signaling pathway
B cell receptor signaling pathway
positive regulation of T cell receptor signaling pathway
positive regulation of T cell activation
leukocyte migration
release of sequestered calcium ion into cytosol
regulation of lymphocyte activation
positive regulation of intrinsic apoptotic signaling pathway
glycoprotein binding
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein serine/threonine phosphatase activity
protein binding
ATP binding
protein C-terminus binding
kinase activity
protein kinase binding
protein phosphatase binding
SH2 domain binding
CD4 receptor binding
CD8 receptor binding
identical protein binding
phosphatidylinositol 3-kinase binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
ATPase binding

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