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Gene Symbol:
TP53
Gene Name:
tumor protein p53
Gene Aliases:
BCC7, LFS1, P53, TRP53
Chromosome Location:
Chr.17: 7668402 - 7687550 on Build GRCh38
UniGene ID:
Hs.437460
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s606
Validated

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Catalog # 4390824
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: TP53
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000546.5 NP_000537.3 6 806
NM_001126112.2 NP_001119584.1 6 803
NM_001126113.2 NP_001119585.1 6 806
NM_001126114.2 NP_001119586.1 6 806
NM_001126115.1 NP_001119587.1 2 486
NM_001126116.1 NP_001119588.1 2 486
NM_001126117.1 NP_001119589.1 2 486
NM_001126118.1 NP_001119590.1 5 923
NM_001276695.1 NP_001263624.1 6 806
NM_001276696.1 NP_001263625.1 6 806
NM_001276697.1 NP_001263626.1 2 486
NM_001276698.1 NP_001263627.1 2 486
NM_001276699.1 NP_001263628.1 2 486
NM_001276760.1 NP_001263689.1 6 806
NM_001276761.1 NP_001263690.1 6 803
GenBank mRNA AB082923.1 - 6 667
AF307851.1 - 6 739
AK225838.1 - 6 744
AK297462.1 - 7 671
AK297927.1 - 7 716
AK303277.1 - 5 862
AK312568.1 - 6 748
AM076970.1 - 5 571
AM076971.1 - 5 604
AM076972.1 - 5 604
AY429684.1 - 5 604
BC003596.1 - 6 724 3544714
BT019622.1 - 5 604
DQ186648.1 - 6 736
DQ186649.1 - 6 736
DQ186650.1 - 2 482
DQ186651.1 - 2 482
DQ186652.1 - 2 482
DQ191317.1 - 6 793
DQ263704.1 - 5 604
DQ286964.1 - 6 738
DQ648884.1 - 5 404
DQ648885.1 - 3 280
EF101867.1 - 5 571
EF101868.1 - 5 604
EF101869.1 - 5 604
JN214348.1 - 5 649
JN601513.1 - 5 604
JN601514.1 - 5 604
JN601515.1 - 5 604
JN601516.1 - 6 578
JN900492.1 - 5 912
JQ026207.1 - 5 594
JQ026208.1 - 5 599
JQ026209.1 - 5 604
JQ026210.1 - 5 604
JQ694049.1 - 5 627
JQ694050.1 - 5 627
JQ694051.1 - 5 627
KC820708.1 - 2 99
KC820709.1 - 2 99
KC820710.1 - 2 99
KC820711.1 - 2 99
KC820712.1 - 2 99
KC820713.1 - 2 99
KC820714.1 - 2 99
KC820715.1 - 2 99
KC820716.1 - 2 99
KC820717.1 - 2 99
KC820718.1 - 2 99
KC820719.1 - 2 99
KC820720.1 - 2 99
KC820721.1 - 2 99
KC820722.1 - 2 99
KC820723.1 - 2 99
KC820724.1 - 2 99
KC820725.1 - 2 99
KC820726.1 - 2 99
KC820727.1 - 2 99
KC820728.1 - 2 99
KC820729.1 - 2 99
KC820730.1 - 2 99
KC820731.1 - 2 99
KC820732.1 - 2 99
KC820733.1 - 2 99
KC820734.1 - 2 99
KC820735.1 - 2 99
KC820736.1 - 2 99
KC820737.1 - 2 99
KC820738.1 - 2 99
KC820739.1 - 2 99
KC820740.1 - 2 99
KC820741.1 - 2 99
KC820742.1 - 2 99
KC820743.1 - 2 99
KC820744.1 - 2 99
KC820745.1 - 2 99
KC820746.1 - 2 99
KC820747.1 - 2 99
KC820748.1 - 2 99
KC820749.1 - 2 99
KC820750.1 - 2 99
KC820751.1 - 2 99
KC820752.1 - 2 99
KC820753.1 - 2 99
KC820754.1 - 2 99
KC820755.1 - 2 99
KC820756.1 - 2 99
KC820757.1 - 2 99
KC820758.1 - 2 99
KC820760.1 - 2 99
KC820761.1 - 2 99
KC820762.1 - 2 99
KC820763.1 - 2 99
KC820764.1 - 2 99
KC820765.1 - 2 99
KC820766.1 - 2 99
KC820767.1 - 2 99
KC820768.1 - 2 99
KC820769.1 - 2 99
KC820770.1 - 2 99
KC820771.1 - 2 99
KC820772.1 - 2 99
KC820773.1 - 2 99
KC820774.1 - 2 99
KC820775.1 - 2 99
KC820776.1 - 2 99
KC820777.1 - 2 99
KC820778.1 - 2 99
KC820779.1 - 2 99
KC820780.1 - 2 99
KC820781.1 - 2 99
KC820782.1 - 2 99
KC820783.1 - 2 99
KC820784.1 - 2 99
KC820785.1 - 2 99
KC820786.1 - 2 99
M14694.1 - 6 729
M14695.1 - 6 725
X01405.1 - 3 305
X02469.1 - 6 739
X60010.1 - 5 603
X60011.1 - 5 604
X60012.1 - 5 604
X60013.1 - 5 604
X60014.1 - 5 604
X60015.1 - 5 604
X60016.1 - 5 604
X60017.1 - 5 604
X60018.1 - 5 604
X60019.1 - 5 604
X60020.1 - 5 604

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_003749209.

Matching Taqman Gene Expression Assay:


Hs00153340_m1

Panther Classification:

Molecular Function -

P53-like transcription factor

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA strand renaturation
base-excision repair
nucleotide-excision repair
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ER overload response
cell cycle arrest
Ras protein signal transduction
multicellular organism development
cell aging
protein localization
cell proliferation
negative regulation of cell proliferation
determination of adult lifespan
response to X-ray
response to gamma radiation
positive regulation of gene expression
viral process
protein sumoylation
cell differentiation
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
positive regulation of histone deacetylation
chromatin assembly
mitotic G1 DNA damage checkpoint
positive regulation of protein oligomerization
cellular response to UV
cellular response to drug
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to antibiotic
positive regulation of protein export from nucleus
regulation of mitochondrial membrane permeability
negative regulation of fibroblast proliferation
circadian behavior
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of helicase activity
protein tetramerization
negative regulation of telomerase activity
positive regulation of thymocyte apoptotic process
positive regulation of cell cycle arrest
cellular response to hypoxia
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
replicative senescence
oxidative stress-induced premature senescence
intrinsic apoptotic signaling pathway
oligodendrocyte apoptotic process
positive regulation of execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
regulation of cell cycle G2/M phase transition
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of reactive oxygen species metabolic process
positive regulation of intrinsic apoptotic signaling pathway
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protease binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
copper ion binding
protein binding
ATP binding
transcription factor binding
zinc ion binding
enzyme binding
protein kinase binding
protein phosphatase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
histone acetyltransferase binding
identical protein binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
chaperone binding
protein phosphatase 2A binding

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