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Gene Symbol:
TP53
Gene Name:
tumor protein p53
Gene Aliases:
BCC7, LFS1, P53, TRP53
Chromosome Location:
Chr.17: 7668402 - 7687550 on Build GRCh38
UniGene ID:
Hs.437460
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s605
Validated

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Catalog # 4390824
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: TP53
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000546.5 NP_000537.3 7, 8 995
NM_001126112.2 NP_001119584.1 7, 8 992
NM_001126113.2 NP_001119585.1 7, 8 995
NM_001126114.2 NP_001119586.1 7, 8 995
NM_001126115.1 NP_001119587.1 3, 4 675
NM_001126116.1 NP_001119588.1 3, 4 675
NM_001126117.1 NP_001119589.1 3, 4 675
NM_001126118.1 NP_001119590.1 6, 7 1112
NM_001276695.1 NP_001263624.1 7, 8 995
NM_001276696.1 NP_001263625.1 7, 8 995
NM_001276697.1 NP_001263626.1 3, 4 675
NM_001276698.1 NP_001263627.1 3, 4 675
NM_001276699.1 NP_001263628.1 3, 4 675
NM_001276760.1 NP_001263689.1 7, 8 995
NM_001276761.1 NP_001263690.1 7, 8 992
GenBank mRNA AB082923.1 - 7, 8 856
AF307851.1 - 7, 8 928
AK223026.1 - 1, 2 88
AK225838.1 - 7, 8 933
AK297462.1 - 8, 9 860
AK297927.1 - 8, 9 905
AK312568.1 - 7, 8 937
AM076970.1 - 6, 7 760
AM076972.1 - 6, 7 793
AY429684.1 - 6, 7 793
BC003596.1 - 7, 8 913 3544714
BT019622.1 - 6, 7 793
DQ186648.1 - 7, 8 925
DQ186649.1 - 7, 8 925
DQ186650.1 - 3, 4 671
DQ186651.1 - 3, 4 671
DQ186652.1 - 3, 4 671
DQ191317.1 - 7, 8 982
DQ286964.1 - 7, 8 927
EF101867.1 - 6, 7 760
EF101868.1 - 6, 7 793
FJ207420.1 - 7, 8 928
JN214348.1 - 6, 7 838
JN601513.1 - 6, 7 793
JN601514.1 - 6, 7 793
JN601515.1 - 6, 7 793
JN601516.1 - 7, 8 767
JN900492.1 - 6, 7 1101
JQ026207.1 - 6, 7 783
JQ026208.1 - 6, 7 788
JQ026209.1 - 6, 7 798
JQ694049.1 - 6, 7 816
JQ694050.1 - 6, 7 816
JQ694051.1 - 6, 7 816
KC820708.1 - 3, 4 288
KC820709.1 - 3, 4 288
KC820710.1 - 3, 4 288
KC820711.1 - 3, 4 288
KC820712.1 - 3, 4 288
KC820713.1 - 3, 4 288
KC820714.1 - 3, 4 288
KC820715.1 - 3, 4 288
KC820716.1 - 3, 4 288
KC820717.1 - 3, 4 288
KC820718.1 - 3, 4 288
KC820719.1 - 3, 4 288
KC820720.1 - 3, 4 288
KC820721.1 - 3, 4 288
KC820722.1 - 3, 4 288
KC820723.1 - 3, 4 288
KC820724.1 - 3, 4 288
KC820725.1 - 3, 4 288
KC820726.1 - 3, 4 288
KC820727.1 - 3, 4 288
KC820728.1 - 3, 4 288
KC820729.1 - 3, 4 288
KC820730.1 - 3, 4 288
KC820731.1 - 3, 4 288
KC820732.1 - 3, 4 288
KC820733.1 - 3, 4 288
KC820734.1 - 3, 4 288
KC820735.1 - 3, 4 288
KC820736.1 - 3, 4 288
KC820737.1 - 3, 4 288
KC820738.1 - 3, 4 288
KC820740.1 - 3, 4 288
KC820741.1 - 3, 4 288
KC820742.1 - 3, 4 288
KC820743.1 - 3, 4 288
KC820744.1 - 3, 4 288
KC820745.1 - 3, 4 288
KC820746.1 - 3, 4 288
KC820747.1 - 3, 4 288
KC820748.1 - 3, 4 288
KC820749.1 - 3, 4 288
KC820750.1 - 3, 4 288
KC820751.1 - 3, 4 288
KC820752.1 - 3, 4 288
KC820753.1 - 3, 4 288
KC820754.1 - 3, 4 288
KC820755.1 - 3, 4 288
KC820756.1 - 3, 4 288
KC820757.1 - 3, 4 288
KC820758.1 - 3, 4 288
KC820759.1 - 2, 3 177
KC820760.1 - 3, 4 288
KC820761.1 - 3, 4 288
KC820762.1 - 3, 4 288
KC820763.1 - 3, 4 288
KC820764.1 - 3, 4 288
KC820765.1 - 3, 4 288
KC820766.1 - 3, 4 288
KC820767.1 - 3, 4 288
KC820768.1 - 3, 4 288
KC820769.1 - 3, 4 288
KC820770.1 - 3, 4 288
KC820771.1 - 3, 4 288
KC820772.1 - 3, 4 288
KC820773.1 - 3, 4 288
KC820774.1 - 3, 4 288
KC820775.1 - 3, 4 288
KC820776.1 - 3, 4 288
KC820777.1 - 3, 4 288
KC820778.1 - 3, 4 288
KC820779.1 - 3, 4 288
KC820780.1 - 3, 4 288
KC820781.1 - 3, 4 288
KC820782.1 - 3, 4 288
KC820783.1 - 3, 4 288
KC820784.1 - 3, 4 288
KC820785.1 - 3, 4 288
KC820786.1 - 3, 4 288
M14694.1 - 7, 8 918
M14695.1 - 7, 8 914
X01405.1 - 4, 5 494
X02469.1 - 7, 8 928
X60011.1 - 6, 7 793
X60012.1 - 6, 7 793
X60013.1 - 6, 7 793
X60014.1 - 6, 7 793
X60015.1 - 6, 7 793
X60016.1 - 6, 7 793
X60017.1 - 6, 7 793
X60018.1 - 6, 7 793
X60019.1 - 6, 7 793
X60020.1 - 6, 7 793

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_003749209.

Matching Taqman Gene Expression Assay:


Hs00153340_m1

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA strand renaturation
base-excision repair
nucleotide-excision repair
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ER overload response
cell cycle arrest
Ras protein signal transduction
multicellular organism development
cell aging
protein localization
cell proliferation
negative regulation of cell proliferation
determination of adult lifespan
response to X-ray
response to gamma radiation
positive regulation of gene expression
viral process
protein sumoylation
cell differentiation
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
positive regulation of histone deacetylation
chromatin assembly
mitotic G1 DNA damage checkpoint
positive regulation of protein oligomerization
cellular response to UV
cellular response to drug
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to antibiotic
positive regulation of protein export from nucleus
regulation of mitochondrial membrane permeability
negative regulation of fibroblast proliferation
circadian behavior
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of helicase activity
protein tetramerization
negative regulation of telomerase activity
positive regulation of thymocyte apoptotic process
positive regulation of cell cycle arrest
cellular response to hypoxia
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
replicative senescence
oxidative stress-induced premature senescence
intrinsic apoptotic signaling pathway
oligodendrocyte apoptotic process
positive regulation of execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
regulation of cell cycle G2/M phase transition
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of reactive oxygen species metabolic process
positive regulation of intrinsic apoptotic signaling pathway
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protease binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
copper ion binding
protein binding
ATP binding
transcription factor binding
zinc ion binding
enzyme binding
protein kinase binding
protein phosphatase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
histone acetyltransferase binding
identical protein binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
chaperone binding
protein phosphatase 2A binding

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