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Gene Symbol:
TP53
Gene Name:
tumor protein p53
Gene Aliases:
BCC7, LFS1, P53, TRP53
Chromosome Location:
Chr.17: 7668402 - 7687550 on Build GRCh38
UniGene ID:
Hs.437460
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s536424

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Catalog # 4392420
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: TP53
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000546.5 NP_000537.3 7, 8 984
NM_001126112.2 NP_001119584.1 7, 8 981
NM_001126113.2 NP_001119585.1 7, 8 984
NM_001126114.2 NP_001119586.1 7, 8 984
NM_001126115.1 NP_001119587.1 3, 4 664
NM_001126116.1 NP_001119588.1 3, 4 664
NM_001126117.1 NP_001119589.1 3, 4 664
NM_001126118.1 NP_001119590.1 6, 7 1101
NM_001276695.1 NP_001263624.1 7, 8 984
NM_001276696.1 NP_001263625.1 7, 8 984
NM_001276697.1 NP_001263626.1 3, 4 664
NM_001276698.1 NP_001263627.1 3, 4 664
NM_001276699.1 NP_001263628.1 3, 4 664
NM_001276760.1 NP_001263689.1 7, 8 984
NM_001276761.1 NP_001263690.1 7, 8 981
GenBank mRNA AB082923.1 - 7, 8 845
AF307851.1 - 7, 8 917
AK223026.1 - 1, 2 77
AK225838.1 - 7, 8 922
AK297462.1 - 8, 9 849
AK297927.1 - 8, 9 894
AK312568.1 - 7, 8 926
AM076970.1 - 6, 7 749
AM076972.1 - 6, 7 782
AY429684.1 - 6, 7 782
BC003596.1 - 7, 8 902 3544714
BT019622.1 - 6, 7 782
DQ186648.1 - 7, 8 914
DQ186649.1 - 7, 8 914
DQ186650.1 - 3, 4 660
DQ186651.1 - 3, 4 660
DQ186652.1 - 3, 4 660
DQ191317.1 - 7, 8 971
DQ263704.1 - 6, 7 782
DQ286964.1 - 7, 8 916
EF101867.1 - 6, 7 749
EF101868.1 - 6, 7 782
FJ207420.1 - 7, 8 917
JN214348.1 - 6, 7 827
JN601513.1 - 6, 7 782
JN601514.1 - 6, 7 782
JN601515.1 - 6, 7 782
JN601516.1 - 7, 8 756
JN900492.1 - 6, 7 1090
JQ026207.1 - 6, 7 772
JQ026208.1 - 6, 7 777
JQ026209.1 - 6, 7 787
JQ694049.1 - 6, 7 805
JQ694050.1 - 6, 7 805
JQ694051.1 - 6, 7 805
KC820708.1 - 3, 4 277
KC820709.1 - 3, 4 277
KC820710.1 - 3, 4 277
KC820711.1 - 3, 4 277
KC820712.1 - 3, 4 277
KC820713.1 - 3, 4 277
KC820714.1 - 3, 4 277
KC820715.1 - 3, 4 277
KC820716.1 - 3, 4 277
KC820717.1 - 3, 4 277
KC820718.1 - 3, 4 277
KC820719.1 - 3, 4 277
KC820720.1 - 3, 4 277
KC820721.1 - 3, 4 277
KC820722.1 - 3, 4 277
KC820723.1 - 3, 4 277
KC820724.1 - 3, 4 277
KC820725.1 - 3, 4 277
KC820726.1 - 3, 4 277
KC820727.1 - 3, 4 277
KC820728.1 - 3, 4 277
KC820729.1 - 3, 4 277
KC820730.1 - 3, 4 277
KC820731.1 - 3, 4 277
KC820732.1 - 3, 4 277
KC820733.1 - 3, 4 277
KC820734.1 - 3, 4 277
KC820735.1 - 3, 4 277
KC820736.1 - 3, 4 277
KC820737.1 - 3, 4 277
KC820738.1 - 3, 4 277
KC820739.1 - 3, 4 277
KC820740.1 - 3, 4 277
KC820741.1 - 3, 4 277
KC820742.1 - 3, 4 277
KC820743.1 - 3, 4 277
KC820744.1 - 3, 4 277
KC820745.1 - 3, 4 277
KC820746.1 - 3, 4 277
KC820747.1 - 3, 4 277
KC820748.1 - 3, 4 277
KC820749.1 - 3, 4 277
KC820750.1 - 3, 4 277
KC820751.1 - 3, 4 277
KC820752.1 - 3, 4 277
KC820753.1 - 3, 4 277
KC820754.1 - 3, 4 277
KC820755.1 - 3, 4 277
KC820756.1 - 3, 4 277
KC820757.1 - 3, 4 277
KC820758.1 - 3, 4 277
KC820759.1 - 2, 3 166
KC820760.1 - 3, 4 277
KC820761.1 - 3, 4 277
KC820762.1 - 3, 4 277
KC820763.1 - 3, 4 277
KC820764.1 - 3, 4 277
KC820765.1 - 3, 4 277
KC820766.1 - 3, 4 277
KC820767.1 - 3, 4 277
KC820768.1 - 3, 4 277
KC820769.1 - 3, 4 277
KC820770.1 - 3, 4 277
KC820771.1 - 3, 4 277
KC820772.1 - 3, 4 277
KC820773.1 - 3, 4 277
KC820774.1 - 3, 4 277
KC820775.1 - 3, 4 277
KC820776.1 - 3, 4 277
KC820777.1 - 3, 4 277
KC820778.1 - 3, 4 277
KC820779.1 - 3, 4 277
KC820780.1 - 3, 4 277
KC820781.1 - 3, 4 277
KC820782.1 - 3, 4 277
KC820783.1 - 3, 4 277
KC820784.1 - 3, 4 277
KC820785.1 - 3, 4 277
KC820786.1 - 3, 4 277
M14694.1 - 7, 8 907
M14695.1 - 7, 8 903
X01405.1 - 4, 5 483
X02469.1 - 7, 8 917
X60011.1 - 6, 7 782
X60012.1 - 6, 7 782
X60013.1 - 6, 7 782
X60014.1 - 6, 7 782
X60015.1 - 6, 7 782
X60016.1 - 6, 7 782
X60017.1 - 6, 7 782
X60018.1 - 6, 7 782
X60019.1 - 6, 7 782
X60020.1 - 6, 7 782

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: XM_003749209.

Panther Classification:

Molecular Function -

P53-like transcription factor

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA strand renaturation
base-excision repair
nucleotide-excision repair
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ER overload response
cell cycle arrest
Ras protein signal transduction
multicellular organism development
cell aging
protein localization
cell proliferation
negative regulation of cell proliferation
determination of adult lifespan
response to X-ray
response to gamma radiation
positive regulation of gene expression
viral process
protein sumoylation
cell differentiation
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
positive regulation of histone deacetylation
chromatin assembly
mitotic G1 DNA damage checkpoint
positive regulation of protein oligomerization
cellular response to UV
cellular response to drug
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to antibiotic
positive regulation of protein export from nucleus
regulation of mitochondrial membrane permeability
negative regulation of fibroblast proliferation
circadian behavior
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of helicase activity
protein tetramerization
negative regulation of telomerase activity
positive regulation of thymocyte apoptotic process
positive regulation of cell cycle arrest
cellular response to hypoxia
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
replicative senescence
oxidative stress-induced premature senescence
intrinsic apoptotic signaling pathway
oligodendrocyte apoptotic process
positive regulation of execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
regulation of cell cycle G2/M phase transition
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of reactive oxygen species metabolic process
positive regulation of intrinsic apoptotic signaling pathway
RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protease binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
copper ion binding
protein binding
ATP binding
transcription factor binding
zinc ion binding
enzyme binding
protein kinase binding
protein phosphatase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
histone acetyltransferase binding
identical protein binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
chaperone binding
protein phosphatase 2A binding

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