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See other APOE SIRNA Assays ›
Gene Symbol:
APOE
Gene Name:
apolipoprotein E
Gene Aliases:
AD2, APO-E, LDLCQ5, LPG
Chromosome Location:
Chr.19: 44905749 - 44909395 on Build GRCh38
UniGene ID:
Hs.654439
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s536402

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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: APOE
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000041.3 NP_000032.1 4 391
NM_001302688.1 NP_001289617.1 4 473
NM_001302689.1 NP_001289618.1 4 322
NM_001302690.1 NP_001289619.1 4 422
NM_001302691.1 NP_001289620.1 4 406
GenBank mRNA AK314898.1 - 4 344
BC003557.1 - 4 320 3355712
BI550631.1 - 4 368
BM042032.1 - 4 406
BU848796.1 - 358
CA771535.1 - 3 540
HY056112.1 - 4 391
HY074384.1 - 4 322
HY074888.1 - 4 422
K00396.1 - 4 335
KU177910.1 - 3 275
KU177911.1 - 3 275
M12529.1 - 4 336
X00199.1 - 2 86

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More Information


Gene Ontology Categories:

Function(s) Process(es)

response to reactive oxygen species
retinoid metabolic process
negative regulation of endothelial cell proliferation
response to dietary excess
triglyceride metabolic process
cholesterol catabolic process
cellular calcium ion homeostasis
receptor-mediated endocytosis
cytoskeleton organization
G-protein coupled receptor signaling pathway
nitric oxide mediated signal transduction
synaptic transmission, cholinergic
cholesterol metabolic process
regulation of gene expression
negative regulation of platelet activation
positive regulation of cholesterol esterification
positive regulation of cholesterol efflux
long-chain fatty acid transport
protein import
virion assembly
triglyceride catabolic process
cGMP-mediated signaling
negative regulation of blood coagulation
regulation of axon extension
positive regulation of cGMP biosynthetic process
neuron projection regeneration
regulation of Cdc42 protein signal transduction
positive regulation of low-density lipoprotein particle receptor catabolic process
cholesterol efflux
phospholipid efflux
very-low-density lipoprotein particle remodeling
low-density lipoprotein particle remodeling
high-density lipoprotein particle remodeling
high-density lipoprotein particle assembly
chylomicron remnant clearance
high-density lipoprotein particle clearance
very-low-density lipoprotein particle clearance
lipoprotein metabolic process
lipoprotein biosynthetic process
lipoprotein catabolic process
vasodilation
cholesterol homeostasis
negative regulation of MAP kinase activity
negative regulation of neuron apoptotic process
negative regulation of blood vessel endothelial cell migration
reverse cholesterol transport
positive regulation by host of viral process
negative regulation of cholesterol biosynthetic process
positive regulation of lipid biosynthetic process
intracellular transport
regulation of neuronal synaptic plasticity
artery morphogenesis
negative regulation of inflammatory response
positive regulation of nitric-oxide synthase activity
positive regulation of membrane protein ectodomain proteolysis
maintenance of location in cell
fatty acid homeostasis
positive regulation of dendritic spine development
negative regulation of canonical Wnt signaling pathway
AMPA glutamate receptor clustering
NMDA glutamate receptor clustering
cellular oxidant detoxification
regulation of beta-amyloid clearance
negative regulation of neuron death
positive regulation of postsynaptic membrane organization
negative regulation of presynaptic membrane organization
negative regulation of beta-amyloid formation
positive regulation of dendritic spine maintenance
positive regulation of phospholipid efflux
positive regulation of lipid transport across blood brain barrier
beta-amyloid binding
lipid transporter activity
protein binding
phospholipid binding
heparin binding
lipid binding
cholesterol binding
antioxidant activity
cholesterol transporter activity
identical protein binding
protein homodimerization activity
metal chelating activity
tau protein binding
low-density lipoprotein particle receptor binding
phosphatidylcholine-sterol O-acyltransferase activator activity
very-low-density lipoprotein particle receptor binding
lipoprotein particle binding

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