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Gene Symbol:
ERCC2
Gene Name:
ERCC excision repair 2, TFIIH core complex helicase subunit
Gene Aliases:
COFS2, EM9, TFIIH, TTD, TTD1, XPD
Chromosome Location:
Chr.19: 45349837 - 45370647 on Build GRCh38
UniGene ID:
Hs.487294
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s534580

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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: ERCC2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000400.3 NP_000391.1 9, 10 870
NM_001130867.1 NP_001124339.1 8, 9 1173
XM_011526611.2 XP_011524913.1 8, 9 852
XM_017026467.1 XP_016881956.1 8, 9 766
GenBank mRNA AK303358.1 - 6, 7 482
AL535248.3 - 9, 10 896
BC008346.1 - 8, 9 970
BC108255.1 - 9, 10 833 6044425
BC110522.1 - 7, 8 617 40034047
BC110523.1 - 9, 10 851 40034048
BT006883.1 - 8, 9 751
X52221.1 - 8, 9 1504

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More Information


Gene Ontology Categories:

Function(s) Process(es)

nucleotide-excision repair, DNA duplex unwinding
response to hypoxia
in utero embryonic development
transcription-coupled nucleotide-excision repair
nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
protein phosphorylation
apoptotic process
response to oxidative stress
chromosome segregation
aging
cell proliferation
UV protection
post-embryonic development
viral process
spinal cord development
extracellular matrix organization
bone mineralization
central nervous system myelin formation
nucleotide-excision repair, DNA incision
multicellular organism growth
hair cell differentiation
embryonic cleavage
erythrocyte maturation
positive regulation of DNA binding
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
hair follicle maturation
hematopoietic stem cell differentiation
global genome nucleotide-excision repair
regulation of mitotic cell cycle phase transition
DNA binding
ATP-dependent DNA helicase activity
protein kinase activity
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
RNA polymerase II carboxy-terminal domain kinase activity
5'-3' DNA helicase activity
metal ion binding
protein N-terminus binding
4 iron, 4 sulfur cluster binding

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