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Gene Symbol:
NLRP3
Gene Name:
NLR family pyrin domain containing 3
Gene Aliases:
AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCAS1, FCU, MWS, NALP3, PYPAF1
Chromosome Location:
Chr.1: 247416156 - 247449108 on Build GRCh38
UniGene ID:
Hs.159483
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s534397

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Catalog # 4392420
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: NLRP3
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001079821.2 NP_001073289.1 5 1657
NM_001127461.2 NP_001120933.1 4 2299
NM_001127462.2 NP_001120934.1 3 2265
NM_001243133.1 NP_001230062.1 3 2265
NM_004895.4 NP_004886.3 3 2265
NM_183395.2 NP_899632.1 3 2265
XM_011544048.2 XP_011542350.1 4 2404
XM_011544053.2 XP_011542355.1 4 2292
XM_011544055.2 XP_011542357.1 4 2292
XM_017000181.1 XP_016855670.1 5 1881
XM_017000182.1 XP_016855671.1 5 1826
XM_017000183.1 XP_016855672.1 4 2292
XM_017000184.1 XP_016855673.1 4 2292
GenBank mRNA AB208891.1 - 3 2274
AF054176.1 - 1 344
AF410477.1 - 3 2265
AF418985.2 - 3 1681
AF420469.1 - 4 1651
AF427617.1 - 3 2265
AF468522.1 - 3 1681
AK027194.1 - 3 1695
AK314998.1 - 5 1657
AY092033.1 - 3 1681
AY422168.1 - 3 1513
BC117211.1 - 3 1584 40125762
BC143359.1 - 3 1584 9051864
BC143362.1 - 3 1584 9051867
BC143363.1 - 3 1584 9051868

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More Information


Gene Ontology Categories:

Function(s) Process(es)

negative regulation of acute inflammatory response
positive regulation of type 2 immune response
transcription, DNA-templated
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
defense response
inflammatory response
signal transduction
detection of biotic stimulus
negative regulation of NF-kappaB transcription factor activity
interleukin-1 beta production
interleukin-18 production
positive regulation of interleukin-13 production
positive regulation of interleukin-4 production
positive regulation of interleukin-5 production
negative regulation of NF-kappaB import into nucleus
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
NLRP3 inflammasome complex assembly
innate immune response
positive regulation of T-helper 2 cell differentiation
positive regulation of transcription from RNA polymerase II promoter
interleukin-1 secretion
negative regulation of interleukin-1 beta secretion
positive regulation of interleukin-1 beta secretion
negative regulation of inflammatory response
positive regulation of NF-kappaB transcription factor activity
protein oligomerization
defense response to virus
cellular response to lipopolysaccharide
positive regulation of T-helper 17 cell differentiation
positive regulation of T-helper 2 cell cytokine production
protein binding
ATP binding
transcription factor binding
peptidoglycan binding
sequence-specific DNA binding

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