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Gene Symbol:
MSH2
Gene Name:
mutS homolog 2
Gene Aliases:
COCA1, FCC1, HNPCC, HNPCC1, LCFS2
Chromosome Location:
Chr.2: 47403067 - 47634501 on Build GRCh38
UniGene ID:
Hs.597656
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s534361

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Catalog # 4392420
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: MSH2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_000251.2 NP_000242.1 10 1768
NM_001258281.1 NP_001245210.1 11 1584
XM_005264332.3 XP_005264389.2 10 1715
XM_011532867.1 XP_011531169.1 10 1715
GenBank mRNA AK222860.1 - 10 1705
AK223284.1 - 10 1678
AK296831.1 - 9 1243
AK297763.1 - 10 1471
AK299667.1 - 9 1103
AK304496.1 - 11 1584
BC021566.1 - 10 1657 4110354
BX649122.1 - 10 1663
L47574.1 - 10 1683
L47575.1 - 10 1681
L47576.1 - 10 1682
L47577.1 - 10 1683
L47578.1 - 10 1684
L47579.1 - 10 1684
L47580.1 - 10 1683
L47581.1 - 10 1683
L47582.1 - 10 1683
L47583.1 - 10 1683
U03911.1 - 10 1646
U04045.1 - 10 1711

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More Information


Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Function(s) Process(es)

meiotic mismatch repair
in utero embryonic development
oxidative phosphorylation
DNA repair
mismatch repair
postreplication repair
double-strand break repair
meiotic gene conversion
cell cycle arrest
reciprocal meiotic recombination
germ cell development
determination of adult lifespan
male gonad development
response to X-ray
response to UV-B
somatic hypermutation of immunoglobulin genes
somatic recombination of immunoglobulin gene segments
B cell mediated immunity
B cell differentiation
intra-S DNA damage checkpoint
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
negative regulation of neuron apoptotic process
maintenance of DNA repeat elements
negative regulation of reciprocal meiotic recombination
isotype switching
negative regulation of DNA recombination
positive regulation of helicase activity
magnesium ion binding
four-way junction DNA binding
Y-form DNA binding
heteroduplex DNA loop binding
double-strand/single-strand DNA junction binding
DNA binding
double-stranded DNA binding
single-stranded DNA binding
protein binding
ATP binding
protein C-terminus binding
ATPase activity
centromeric DNA binding
enzyme binding
protein kinase binding
mismatched DNA binding
guanine/thymine mispair binding
dinucleotide insertion or deletion binding
single guanine insertion binding
single thymine insertion binding
dinucleotide repeat insertion binding
oxidized purine DNA binding
MutLalpha complex binding
protein homodimerization activity
ADP binding

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