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Gene Symbol:
DOT1L
Gene Name:
DOT1 like histone lysine methyltransferase
Gene Aliases:
DOT1, KMT4
Chromosome Location:
Chr.19: 2163963 - 2232578 on Build GRCh38
UniGene ID:
Hs.713641
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s39012

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Catalog # 4392420
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: DOT1L
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_032482.2 NP_115871.1 11, 12 1003
XM_005259659.3 XP_005259716.1 11, 12 1189
XM_005259660.3 XP_005259717.1 11, 12 1189
XM_011528359.2 XP_011526661.1 11, 12 1189
XM_011528360.1 XP_011526662.1 12, 13 1047
XM_011528361.2 XP_011526663.1 3, 4 408
XM_017027366.1 XP_016882855.1 11, 12 1152
GenBank mRNA AF509504.1 - 11, 12 1003
AK074120.1 - 7, 8 668

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_001108733, XM_006240961, XM_006240960, XM_006240959.
This siRNA also targets the following transcripts in Mouse: NM_199322, AY377920, AY196089, JF508521, AK035144, and others.

Gene Ontology Categories:

Function(s) Process(es)

chromatin silencing
positive regulation of cell proliferation
telomere organization
histone H3-K79 methylation
positive regulation of transcription from RNA polymerase II promoter
regulation of JAK-STAT cascade
regulation of cell cycle
regulation of transcription regulatory region DNA binding
DNA binding
protein binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K79 specific)
histone methyltransferase activity

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