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Gene Symbol:
DICER1
Gene Name:
dicer 1, ribonuclease III
Gene Aliases:
DCR1, Dicer, Dicer1e, HERNA, K12H4.8-LIKE, MNG1, RMSE2
Chromosome Location:
Chr.14: 95086228 - 95158010 on Build GRCh38
UniGene ID:
Hs.738957
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s23756
Validated

Purification
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Catalog # 4390824
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: DICER1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001195573.1 NP_001182502.1 8 1466
NM_001271282.2 NP_001258211.1 9 1654
NM_001291628.1 NP_001278557.1 9 1542
NM_030621.4 NP_085124.2 11 1713
NM_177438.2 NP_803187.1 9 1659
XM_011536599.1 XP_011534901.1 11 1845
XM_011536600.2 XP_011534902.1 11 1720
XM_011536601.2 XP_011534903.1 12 1865
XM_011536602.2 XP_011534904.1 12 1756
XM_011536604.2 XP_011534906.1 8 1541
XM_011536605.2 XP_011534907.1 2 6346
XM_017021120.1 XP_016876609.1 11 2152
XM_017021121.1 XP_016876610.1 9 1547
XM_017021122.1 XP_016876611.1 10 1591
XM_017021123.1 XP_016876612.1 10 2022
GenBank mRNA AB023145.2 - 9 1659
AB028449.1 - 10 1609
AJ132261.2 - 9 1662
BC150287.1 - 9 1659 8860125
HM595745.1 - 8 1430

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More Information


Matching Taqman Gene Expression Assay:


Hs00229023_m1

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
apoptotic DNA fragmentation
negative regulation of Schwann cell proliferation
positive regulation of Schwann cell differentiation
nerve development
production of siRNA involved in RNA interference
targeting of mRNA for destruction involved in RNA interference
gene silencing by RNA
pre-miRNA processing
positive regulation of myelination
peripheral nervous system myelin formation
conversion of ds siRNA to ss siRNA involved in RNA interference
siRNA loading onto RISC involved in RNA interference
production of miRNAs involved in gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA
conversion of ds siRNA to ss siRNA
neuron projection morphogenesis
RNA phosphodiester bond hydrolysis, endonucleolytic
double-stranded RNA binding
helicase activity
endoribonuclease activity
ribonuclease III activity
deoxyribonuclease I activity
protein binding
ATP binding
protein domain specific binding
siRNA binding
metal ion binding
pre-miRNA binding

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