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Gene Symbol:
DICER1
Gene Name:
dicer 1, ribonuclease III
Gene Aliases:
DCR1, Dicer, Dicer1e, HERNA, K12H4.8-LIKE, MNG1, RMSE2
Chromosome Location:
Chr.14: 95086228 - 95158010 on Build GRCh38
UniGene ID:
Hs.738957
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s23754
Validated

Purification
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Catalog # 4390824
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: DICER1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001195573.1 NP_001182502.1 9 1684
NM_001271282.2 NP_001258211.1 10 1872
NM_001291628.1 NP_001278557.1 10 1760
NM_030621.4 NP_085124.2 12 1931
NM_177438.2 NP_803187.1 10 1877
XM_011536599.1 XP_011534901.1 12 2063
XM_011536600.2 XP_011534902.1 12 1938
XM_011536601.2 XP_011534903.1 13 2083
XM_011536602.2 XP_011534904.1 13 1974
XM_011536604.2 XP_011534906.1 9 1759
XM_011536605.2 XP_011534907.1 3 6564
XM_017021120.1 XP_016876609.1 12 2370
XM_017021121.1 XP_016876610.1 10 1765
XM_017021122.1 XP_016876611.1 11 1809
XM_017021123.1 XP_016876612.1 11 2240
GenBank mRNA AB023145.2 - 10 1877
AB028449.1 - 11 1827
AJ132261.2 - 10 1880
BC150287.1 - 10 1877 8860125
HM595745.1 - 9 1648

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More Information


Matching Taqman Gene Expression Assay:


Hs00229023_m1

Gene Ontology Categories:

Function(s) Process(es)

negative regulation of transcription from RNA polymerase II promoter
apoptotic DNA fragmentation
negative regulation of Schwann cell proliferation
positive regulation of Schwann cell differentiation
nerve development
production of siRNA involved in RNA interference
targeting of mRNA for destruction involved in RNA interference
gene silencing by RNA
pre-miRNA processing
positive regulation of myelination
peripheral nervous system myelin formation
conversion of ds siRNA to ss siRNA involved in RNA interference
siRNA loading onto RISC involved in RNA interference
production of miRNAs involved in gene silencing by miRNA
miRNA loading onto RISC involved in gene silencing by miRNA
conversion of ds siRNA to ss siRNA
neuron projection morphogenesis
RNA phosphodiester bond hydrolysis, endonucleolytic
double-stranded RNA binding
helicase activity
endoribonuclease activity
ribonuclease III activity
deoxyribonuclease I activity
protein binding
ATP binding
protein domain specific binding
siRNA binding
metal ion binding
pre-miRNA binding

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