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Gene Symbol:
IKBKB
Gene Name:
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Gene Aliases:
IKK-beta, IKK2, IKKB, IMD15, NFKBIKB
Chromosome Location:
Chr.8: 42271302 - 42332653 on Build GRCh38
UniGene ID:
Hs.597664
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s223927

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Catalog # 4392420
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: IKBKB
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001190720.2 NP_001177649.1 21 2283
NM_001242778.1 NP_001229707.1 21 2311
NM_001556.2 NP_001547.1 22 2406
NR_033818.1 22 2462
NR_033819.1 21 2344
NR_040009.1 22 2353
XM_005273492.3 XP_005273549.1 21 2315
GenBank mRNA AB209090.1 - 19 3475
AF029684.1 - 21 2220
AF031416.1 - 21 2220
AF080158.1 - 22 2363
AK091090.1 - 1 572
AK091297.1 - 16 1802
AK093537.1 - 1 893
AK095687.1 - 1 1591
AK097828.1 - 6 1723
AK298241.1 - 19 1970
AK302723.1 - 21 2267
AK303528.1 - 21 2299
AK316418.1 - 21 2267
BC127663.1 - 4 348
BC141978.1 - 4 348
BC144080.1 - 21 2197
BX648165.1 - 20 2796

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_053355, AF115282.
This siRNA also targets the following transcripts in Mouse: NM_001159774, NM_010546, AF088910, AK150884, AK151888, and others.

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase protein modifying enzyme

Gene Ontology Categories:

Function(s) Process(es)

stimulatory C-type lectin receptor signaling pathway
skeletal muscle contraction
protein phosphorylation
inflammatory response
I-kappaB kinase/NF-kappaB signaling
I-kappaB phosphorylation
positive regulation of cell proliferation
response to virus
response to toxic substance
regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of neuron projection development
cortical actin cytoskeleton organization
neuron projection development
response to lipopolysaccharide
tumor necrosis factor-mediated signaling pathway
negative regulation of myosin-light-chain-phosphatase activity
TRIF-dependent toll-like receptor signaling pathway
Fc-epsilon receptor signaling pathway
regulation of phosphorylation
response to drug
serine phosphorylation of STAT protein
negative regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
innate immune response
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
stress-activated MAPK cascade
nucleotide-binding oligomerization domain containing signaling pathway
interleukin-1-mediated signaling pathway
response to fatty acid
cellular response to tumor necrosis factor
establishment of protein localization to plasma membrane
positive regulation of neuron death
regulation of establishment of endothelial barrier
negative regulation of bicellular tight junction assembly
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
IkappaB kinase activity
protein kinase binding
protein homodimerization activity
protein heterodimerization activity
scaffold protein binding

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