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Gene Symbol:
APEX1
Gene Name:
apurinic/apyrimidinic endodeoxyribonuclease 1
Gene Aliases:
APE, APE1, APEN, APEX, APX, HAP1, REF1
Chromosome Location:
Chr.14: 20455131 - 20457772 on Build GRCh38
UniGene ID:
Hs.73722
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s1447
Validated

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Catalog # 4390824
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: APEX1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001244249.1 NP_001231178.1 5 1115
NM_001641.3 NP_001632.2 5 1120
NM_080648.2 NP_542379.1 5 1054
NM_080649.2 NP_542380.1 5 1064
GenBank mRNA AK098588.1 - 5 1004
AK291100.1 - 5 1029
BC002338.2 - 5 1005 2819505
BC004979.1 - 5 917 2905681
BC008145.1 - 5 1003 4180383
BC019291.1 - 5 1005 2823545
BC095428.1 - 6 994 30709297
BT007236.1 - 4 788
BT020133.1 - 4 788
BX161454.1 - 5 954
D90373.1 - 5 993
M80261.1 - 5 910
M81955.1 - 5 998
S43127.1 - 5 1011
U79268.1 - 5 966
X59764.1 - 5 997

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More Information


Matching Taqman Gene Expression Assay:


Hs00172396_m1

Gene Ontology Categories:

Function(s) Process(es)

telomere maintenance
DNA repair
base-excision repair
base-excision repair, base-free sugar-phosphate removal
DNA recombination
transcription, DNA-templated
regulation of transcription, DNA-templated
aging
negative regulation of smooth muscle cell migration
response to drug
regulation of mRNA stability
cell redox homeostasis
positive regulation of DNA repair
oxidation-reduction process
cellular response to hydrogen peroxide
cellular response to cAMP
cellular response to peptide hormone stimulus
DNA demethylation
RNA phosphodiester bond hydrolysis, endonucleolytic
positive regulation of G1/S transition of mitotic cell cycle
negative regulation of nucleic acid-templated transcription
DNA binding
damaged DNA binding
double-stranded telomeric DNA binding
transcription coactivator activity
transcription corepressor activity
DNA-(apurinic or apyrimidinic site) lyase activity
endonuclease activity
endodeoxyribonuclease activity
RNA-DNA hybrid ribonuclease activity
phosphodiesterase I activity
uracil DNA N-glycosylase activity
protein binding
phosphoric diester hydrolase activity
double-stranded DNA exodeoxyribonuclease activity
double-stranded DNA 3'-5' exodeoxyribonuclease activity
3'-5' exonuclease activity
oxidoreductase activity
site-specific endodeoxyribonuclease activity, specific for altered base
chromatin DNA binding
protein complex binding
poly(A) RNA binding
metal ion binding
NF-kappaB binding

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