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Gene Symbol:
TOP2A
Gene Name:
topoisomerase (DNA) II alpha
Gene Aliases:
TOP2, TP2A
Chromosome Location:
Chr.17: 40388521 - 40417950 on Build GRCh38
UniGene ID:
Hs.156346
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s14307
Validated

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Catalog # 4390824
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: TOP2A
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001067.3 NP_001058.2 20 2561
XM_005257632.1 XP_005257689.1 20 2503
XM_011525165.1 XP_011523467.1 20 2507
GenBank mRNA BC013429.1 - 20 2528
BC140791.1 - 20 2431 9021659
J04088.1 - 20 2438

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More Information


Matching Taqman Gene Expression Assay:


Hs00172214_m1

Gene Ontology Categories:

Function(s) Process(es)

resolution of meiotic recombination intermediates
sister chromatid segregation
hematopoietic progenitor cell differentiation
DNA topological change
DNA ligation
DNA unwinding involved in DNA replication
mitotic recombination
cellular response to DNA damage stimulus
chromosome segregation
protein sumoylation
apoptotic chromosome condensation
embryonic cleavage
regulation of circadian rhythm
positive regulation of apoptotic process
mitotic DNA integrity checkpoint
positive regulation of viral genome replication
positive regulation of single stranded viral RNA replication via double stranded DNA intermediate
positive regulation of transcription from RNA polymerase II promoter
rhythmic process
magnesium ion binding
DNA binding
chromatin binding
DNA topoisomerase type II (ATP-hydrolyzing) activity
protein kinase C binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
drug binding
DNA binding, bending
enzyme binding
protein homodimerization activity
histone deacetylase binding
ubiquitin binding
poly(A) RNA binding
protein heterodimerization activity

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