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Gene Symbol:
ROCK1
Gene Name:
Rho associated coiled-coil containing protein kinase 1
Gene Aliases:
P160ROCK, ROCK-I
Chromosome Location:
Chr.18: 20949740 - 21111851 on Build GRCh38
UniGene ID:
Hs.306307
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s12099
Validated

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Catalog # 4390824
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: ROCK1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_005406.2 NP_005397.1 7, 8 1762
GenBank mRNA AK057038.1 - 7, 8 1763
AK307388.1 - 7, 8 1577
BC113114.1 - 7, 8 837 7961989
U43195.1 - 7, 8 821

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_031098, XM_008771957, XM_006254400, XM_006254401, U61266, and others.

Matching Taqman Gene Expression Assay:


Hs00178463_m1

Gene Ontology Categories:

Function(s) Process(es)

apical constriction
protein phosphorylation
cellular component disassembly involved in execution phase of apoptosis
smooth muscle contraction
leukocyte cell-cell adhesion
signal transduction
I-kappaB kinase/NF-kappaB signaling
Rho protein signal transduction
negative regulation of angiogenesis
membrane to membrane docking
actin cytoskeleton organization
regulation of cell adhesion
cortical actin cytoskeleton organization
bleb assembly
negative regulation of protein binding
regulation of actin cytoskeleton organization
negative regulation of myosin-light-chain-phosphatase activity
negative regulation of neuron apoptotic process
regulation of keratinocyte differentiation
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
leukocyte migration
leukocyte tethering or rolling
myoblast migration
regulation of stress fiber assembly
regulation of focal adhesion assembly
positive regulation of focal adhesion assembly
establishment of protein localization to plasma membrane
regulation of establishment of endothelial barrier
negative regulation of bicellular tight junction assembly
regulation of establishment of cell polarity
regulation of cell motility
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
GTP-Rho binding
metal ion binding

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