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Gene Symbol:
PTK2
Gene Name:
protein tyrosine kinase 2
Gene Aliases:
FADK, FAK, FAK1, FRNK, PPP1R71, p125FAK, pp125FAK
Chromosome Location:
Chr.8: 140658382 - 141001313 on Build GRCh38
UniGene ID:
Hs.395482
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s11485
Validated

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Catalog # 4390824
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  • Genomic Map
  • siRNA Details
  • More Information

Genomic Map

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siRNA Details

Gene Symbol: PTK2
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_001199649.1 NP_001186578.1 8 916
NM_001316342.1 NP_001303271.1 6 660
NM_005607.4 NP_005598.3 8 905
NM_153831.3 NP_722560.1 8 916
XM_005251003.2 XP_005251060.1 7 957
XM_005251012.2 XP_005251069.1 7 799
XM_005251013.2 XP_005251070.1 6 618
XM_006716608.2 XP_006716671.1 8 888
XM_006716609.2 XP_006716672.1 7 721
XM_006716610.2 XP_006716673.1 7 713
XM_011517194.2 XP_011515496.1 8 857
XM_017013651.1 XP_016869140.1 6 638
XM_017013652.1 XP_016869141.1 6 638
XM_017013653.1 XP_016869142.1 7 957
XM_017013654.1 XP_016869143.1 7 957
XM_017013655.1 XP_016869144.1 7 957
XM_017013656.1 XP_016869145.1 7 957
XM_017013657.1 XP_016869146.1 7 957
XM_017013658.1 XP_016869147.1 8 781
XM_017013659.1 XP_016869148.1 6 638
XM_017013660.1 XP_016869149.1 8 781
XM_017013661.1 XP_016869150.1 7 799
XM_017013662.1 XP_016869151.1 8 781
XM_017013663.1 XP_016869152.1 7 712
XM_017013664.1 XP_016869153.1 8 888
XM_017013665.1 XP_016869154.1 7 712
XM_017013666.1 XP_016869155.1 7 957
XM_017013667.1 XP_016869156.1 8 781
XM_017013668.1 XP_016869157.1 7 799
XM_017013669.1 XP_016869158.1 8 781
XM_017013670.1 XP_016869159.1 8 781
XM_017013671.1 XP_016869160.1 8 781
XM_017013672.1 XP_016869161.1 7 712
XM_017013673.1 XP_016869162.1 7 712
XM_017013674.1 XP_016869163.1 8 888
XM_017013675.1 XP_016869164.1 7 712
XM_017013676.1 XP_016869165.1 6 638
XM_017013677.1 XP_016869166.1 8 781
XM_017013678.1 XP_016869167.1 7 712
XM_017013679.1 XP_016869168.1 7 712
XM_017013680.1 XP_016869169.1 7 1773
XM_017013681.1 XP_016869170.1 7 721
XM_017013682.1 XP_016869171.1 6 618
XM_017013683.1 XP_016869172.1 7 721
XM_017013684.1 XP_016869173.1 7 721
XM_017013685.1 XP_016869174.1 7 665
XM_017013686.1 XP_016869175.1 6 618
XM_017013687.1 XP_016869176.1 7 721
XM_017013688.1 XP_016869177.1 7 721
XM_017013689.1 XP_016869178.1 6 586
XM_017013690.1 XP_016869179.1 6 560
GenBank mRNA AB209071.1 - 6 566
AB209083.1 - 8 503
AK304356.1 - 8 761
AL832961.1 - 8 788
BC035404.2 - 6 637 4999680
DA994616.1 - 6 519
KF437463.1 - 6 609
L13616.1 - 8 838

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More Information


Other Species Targeted

This siRNA also targets the following transcripts in Rat: NM_013081, XM_008765546, AF020777, EV773243.
This siRNA also targets the following transcripts in Mouse: NM_001130409, NM_007982, AK079821, AB030035, AB011499, and others.

Matching Taqman Gene Expression Assay:


Hs00178587_m1

Gene Ontology Categories:

Function(s) Process(es)

MAPK cascade
microtubule cytoskeleton organization
angiogenesis
vasculogenesis
neuron migration
placenta development
regulation of protein phosphorylation
positive regulation of protein phosphorylation
heart morphogenesis
cellular component disassembly involved in execution phase of apoptosis
signal complex assembly
epidermal growth factor receptor signaling pathway
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
axon guidance
positive regulation of cell proliferation
regulation of cell shape
embryo development
regulation of endothelial cell migration
regulation of epithelial cell migration
positive regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
central nervous system neuron axonogenesis
negative regulation of cell-cell adhesion
establishment of cell polarity
extracellular matrix organization
positive regulation of cell migration
regulation of cell adhesion mediated by integrin
netrin-activated signaling pathway
peptidyl-tyrosine autophosphorylation
Fc-gamma receptor signaling pathway involved in phagocytosis
establishment of nucleus localization
regulation of cell proliferation
negative regulation of apoptotic process
regulation of GTPase activity
endothelial cell migration
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
innate immune response
regulation of osteoblast differentiation
positive regulation of protein kinase activity
negative regulation of organ growth
protein autophosphorylation
vascular endothelial growth factor receptor signaling pathway
ephrin receptor signaling pathway
cell motility
negative regulation of axonogenesis
regulation of cytoskeleton organization
regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
negative regulation of synapse assembly
growth hormone receptor signaling pathway
regulation of substrate adhesion-dependent cell spreading
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of anoikis
actin binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
signal transducer activity
Ras guanyl-nucleotide exchange factor activity
receptor binding
protein binding
ATP binding
JUN kinase binding
protein kinase binding
SH2 domain binding

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