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Gene Symbol:
PIK3R1
Gene Name:
phosphoinositide-3-kinase regulatory subunit 1
Gene Aliases:
AGM7, GRB1, IMD36, p85, p85-ALPHA
Chromosome Location:
Chr.5: 68215737 - 68301821 on Build GRCh38
UniGene ID:
Hs.132225
Species:
Human
Species Specific ID (Flybase ID):
-
siRNA ID s10536
Validated

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Catalog # 4390824
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  • Genomic Map
  • siRNA Details
  • More Information
  • Citations (1)

Genomic Map

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siRNA Details

Gene Symbol: PIK3R1
Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
RefSeq NM_181504.3 NP_852556.2 2 245
NM_181523.2 NP_852664.1 8 1545
NM_181524.1 NP_852665.1 2 377
XM_005248542.3 XP_005248599.1 8 1568
XM_011543493.2 XP_011541795.1 7 1198
XM_017009585.1 XP_016865074.1 8 2337
XM_017009586.1 XP_016865075.1 7 1158
GenBank mRNA AF279367.1 - 2 377
AK000121.1 - 2 291
AK126345.1 - 1 1508
AK223613.1 - 2 225
AK299743.1 - 6 574
BC030815.1 - 2 217 4290954
BC094795.1 - 8 1525 30528412
DA487709.1 - 2 245
M61906.1 - 7 1007

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More Information


Matching Taqman Gene Expression Assay:


Hs00381459_m1

Gene Ontology Categories:

Function(s) Process(es)

cellular glucose homeostasis
negative regulation of cell-matrix adhesion
protein phosphorylation
phosphatidylinositol biosynthetic process
epidermal growth factor receptor signaling pathway
insulin receptor signaling pathway
extrinsic apoptotic signaling pathway via death domain receptors
intrinsic apoptotic signaling pathway in response to DNA damage
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
viral process
platelet activation
B cell differentiation
positive regulation of cell migration
T cell costimulation
positive regulation of tumor necrosis factor production
cellular response to insulin stimulus
positive regulation of RNA splicing
cellular response to UV
response to endoplasmic reticulum stress
phosphatidylinositol-3-phosphate biosynthetic process
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
ERBB2 signaling pathway
positive regulation of transcription factor import into nucleus
negative regulation of apoptotic process
regulation of phosphatidylinositol 3-kinase activity
negative regulation of osteoclast differentiation
positive regulation of transcription from RNA polymerase II promoter
positive regulation of glucose import
phosphatidylinositol phosphorylation
insulin-like growth factor receptor signaling pathway
vascular endothelial growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
protein stabilization
T cell receptor signaling pathway
leukocyte migration
regulation of stress fiber assembly
NFAT protein import into nucleus
growth hormone receptor signaling pathway
positive regulation of establishment of protein localization to plasma membrane
positive regulation of endoplasmic reticulum unfolded protein response
positive regulation of glucose import in response to insulin stimulus
transmembrane receptor protein tyrosine kinase adaptor activity
insulin receptor binding
insulin-like growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
transcription factor binding
1-phosphatidylinositol-3-kinase activity
protein phosphatase binding
phosphatidylinositol 3-kinase regulator activity
phosphatidylinositol 3-kinase regulatory subunit binding
ErbB-3 class receptor binding
phosphatidylinositol 3-kinase binding
insulin binding
insulin receptor substrate binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
1-phosphatidylinositol-3-kinase regulator activity
protein heterodimerization activity

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Citations (1)

Nuclear degradation of Wilms tumor 1-associating protein and survivin splice variant switching underlie IGF-1-mediated survival.
Authors
Small TW, Pickering JG
Journal
J Biol Chem - Page No 24684 (Fri Sep 11 00:00:00 UTC 2009)
Volume (Year)
284 (2009)
Product Usage
-

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